Intrapleural use of tissue plasminogen activator and DNase in pleural infection

Intrapleural use of tissue plasminogen activator and DNase in pleural infection

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BACKGROUND: More than 30% of patients with pleural infection either die or require surgery. Drainage of infected fluid is key to successful treatment, but intrapleural fibrinolytic therapy did not improve outcomes in an earlier, large, randomized trial. METHODS: We conducted a blinded, 2-by-2 factor...

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Main Authors: Rahman, N, Maskell, N, West, A, Teoh, R, Arnold, A, Mackinlay, C, Peckham, D, Davies, C, Ali, N, Kinnear, W, Bentley, A, Kahan, B, Wrightson, J, Davies, H, Hooper, C, Lee, Y, Hedley, E, Crosthwaite, N, Choo, L, Helm, E, Gleeson, F, Nunn, A, Davies, R
Format: Journal article
Sprog:English
Udgivet: 2011

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