Dissecting tunicamycin biosynthesis: a potent carbohydrate processing enzyme inhibitor
<p>Tunicamycin nucleoside antibiotics were the first known to target the formation of peptidoglycan precursor lipid I in bacterial cell wall biosynthesis. They have also been used extensively as inhibitors of protein N-glycosylation in eukaryotes, blocking the biogenesis of early intermediate...
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| Format: | Thesis |
| Language: | English |
| Published: |
2010
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| Subjects: |