mTOR signalling and the regulation of Hoxp3 expression
<p>Regulatory T-cells (Treg) are essential for the establishment of self-tolerance and they can be identified by the expression of FOXP3, the "master" transcription factor for the development of Treg. A number of essential signals, namely TCR engagement, TGFβ, as well as the inhibiti...
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| Formato: | Thesis |
| Idioma: | English |
| Publicado em: |
2013
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