Humanized anti-CD4 monoclonal antibody therapy of autoimmune and inflammatory disease.
We have investigated the biological and therapeutic properties of a humanized anti-CD4 MoAb, hIgG1-CD4, in patients with refractory psoriasis and rheumatoid arthritis (RA). hIgG1-CD4 is a modulating, non-depleting MoAb, which induced a first-dose reaction in most patients treated. It provided brief...
| Autors principals: | , , , , , , , , , , |
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| Format: | Journal article |
| Idioma: | English |
| Publicat: |
1997
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