Humanized anti-CD4 monoclonal antibody therapy of autoimmune and inflammatory disease.

Humanized anti-CD4 monoclonal antibody therapy of autoimmune and inflammatory disease.

We have investigated the biological and therapeutic properties of a humanized anti-CD4 MoAb, hIgG1-CD4, in patients with refractory psoriasis and rheumatoid arthritis (RA). hIgG1-CD4 is a modulating, non-depleting MoAb, which induced a first-dose reaction in most patients treated. It provided brief...

書誌詳細
主要な著者:	Isaacs, J, Burrows, N, Wing, M, Keogan, M, Rebello, P, Watts, R, Pye, R, Norris, P, Hazelman, B, Hale, G, Waldmann, H
フォーマット:	Journal article
言語:	English
出版事項:	1997

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