Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection.

Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection.

Despite substantial advances in our knowledge of immune responses against HIV-1 and of its evolution within the host, it remains unclear why control of the virus eventually breaks down. Here, we present a new theoretical framework for the infection dynamics of HIV-1 that combines antibody and CD8(+)...

Bibliografiset tiedot
Päätekijät:	Wikramaratna, P, Lourenço, J, Klenerman, P, Pybus, O, Gupta, S
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	Royal Society 2015
Aiheet:	Evolution Health and disease and epidemiology Immunology Computational biology Systems biology Theoretical biology

Samankaltaisia teoksia

Delta-Omicron recombinant escapes therapeutic antibody neutralization
Tekijä: Ralf Duerr, et al.
Julkaistu: (2023-02-01)

Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways
Tekijä: Fangzhu Zhao, et al.
Julkaistu: (2022-09-01)

The effect of interference on the CD8+ T cell escape rates in HIV
Tekijä: Victor eGarcia, et al.
Julkaistu: (2015-01-01)

How to make an inclusive-fitness model
Tekijä: Scott, TW, et al.
Julkaistu: (2023)

Adaptive immune evasion in clinically latent HIV infection
Tekijä: Andrews, S
Julkaistu: (2016)

Bispecific antibodies combine breadth, potency, and avidity of parental antibodies to neutralize sarbecoviruses
Tekijä: Laura Radić, et al.
Julkaistu: (2023-04-01)

Nicotinamide breaks effector CD8 T cell responses by targeting mTOR signaling
Tekijä: Federica Agliano, et al.
Julkaistu: (2022-03-01)

Molecular profiling CD8+ T-cell memory inflation
Tekijä: Sims, S, et al.
Julkaistu: (2013)

CD32+CD4+ memory T cells are enriched for total HIV-1 DNA in tissues from humanized mice
Tekijä: Philipp Adams, et al.
Julkaistu: (2021-01-01)

Protocol for generation of human peptide-specific primary CD8+ T cell lines
Tekijä: Emma J. Grant, et al.
Julkaistu: (2022-09-01)

Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env
Tekijä: Edgar A. Hodge, et al.
Julkaistu: (2022-06-01)

The transcription factor IRF4 determines the anti-tumor immunity of CD8+ T cells
Tekijä: Hui Yan, et al.
Julkaistu: (2023-11-01)

Broad SARS-CoV-2 neutralization by monoclonal and bispecific antibodies derived from a Gamma-infected individual
Tekijä: Denise Guerra, et al.
Julkaistu: (2023-10-01)

Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes
Tekijä: Yosuke Harada, et al.
Julkaistu: (2022-04-01)

Biophysics involved in the process of tumor immune escape
Tekijä: Maonan Wang, et al.
Julkaistu: (2022-04-01)

Polyclonal F(ab’)2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency
Tekijä: Luis Eduardo R. Cunha, et al.
Julkaistu: (2021-11-01)

LncRNA TYMSOS facilitates breast cancer metastasis and immune escape through downregulating ULBP3
Tekijä: Ke-Jing Zhang, et al.
Julkaistu: (2023-09-01)

A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies
Tekijä: Evan M. Cale, et al.
Julkaistu: (2024-12-01)

Antigen-specific decidual CD8+ T cells include distinct effector memory and tissue-resident memory cells
Tekijä: Shweta Mahajan, et al.
Julkaistu: (2023-09-01)

Functional assessment of the cell-autonomous role of NADase CD38 in regulating CD8+ T cell exhaustion
Tekijä: Kaili Ma, et al.
Julkaistu: (2022-05-01)

TSC2 S1365A mutation potently regulates CD8+ T cell function and differentiation and improves adoptive cellular cancer therapy
Tekijä: Chirag H. Patel, et al.
Julkaistu: (2023-11-01)

The secret in their MHC: variation and selection in a free living population of great tits
Tekijä: Sepil, I
Julkaistu: (2012)

AP-1/c-Fos supports SIV and HIV-1 latency in CD4 T cells infected in vivo
Tekijä: Viviana Cobos Jiménez, et al.
Julkaistu: (2023-10-01)

Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza
Tekijä: Meito Shibuya, et al.
Julkaistu: (2021-10-01)

YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis
Tekijä: Zhuang Chen, et al.
Julkaistu: (2024-02-01)

The downregulation of IL-18R defines bona fide kidney-resident CD8+ T cells
Tekijä: Wei Liao, et al.
Julkaistu: (2021-01-01)

The poly(C)-binding protein Pcbp2 is essential for CD4+ T cell activation and proliferation
Tekijä: Massimo Martinelli, et al.
Julkaistu: (2023-01-01)

Identification of VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells
Tekijä: Christophe M. Capelle, et al.
Julkaistu: (2021-04-01)

A TLR/CD44 axis regulates T cell trafficking in experimental and human multiple sclerosis
Tekijä: Maria Tredicine, et al.
Julkaistu: (2022-02-01)

The calcitonin receptor protects against bone loss and excessive inflammation in collagen antibody-induced arthritis
Tekijä: Tazio Maleitzke, et al.
Julkaistu: (2022-01-01)

Human RP105 monoclonal antibody enhances antigen-specific antibody production in unique culture conditions
Tekijä: Tatsuya Yamazaki, et al.
Julkaistu: (2024-09-01)

N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody
Tekijä: Arne Zibat, et al.
Julkaistu: (2023-10-01)

Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses
Tekijä: Philip J.M. Brouwer, et al.
Julkaistu: (2024-09-01)

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Tekijä: Willett, BJ, et al.
Julkaistu: (2022)

EP300 restores the glycolytic activity and anti-tumor function of CD8+ cytotoxic T cells in nasopharyngeal carcinoma
Tekijä: Zhixiu Xia, et al.
Julkaistu: (2024-02-01)

Antigen-presenting aged neutrophils induce CD4+ T cells to exacerbate inflammation in sepsis
Tekijä: Hui Jin, et al.
Julkaistu: (2023-07-01)

GRHL2 suppression of NT5E/CD73 in breast cancer cells modulates CD73-mediated adenosine production and T cell recruitment
Tekijä: Bircan Coban, et al.
Julkaistu: (2024-05-01)

Protocol for intracellular immunofluorescence measurements of latent HIV reactivation in a primary CD4+ T cell model
Tekijä: Uri Mbonye, et al.
Julkaistu: (2024-12-01)

CD27hiCD38hi plasmablasts are activated B cells of mixed origin with distinct function
Tekijä: Angeline Rouers, et al.
Julkaistu: (2021-05-01)

Epithelial organoid supports resident memory CD8 T cell differentiation
Tekijä: Max R. Ulibarri, et al.
Julkaistu: (2024-08-01)