Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection.

Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection.

Despite substantial advances in our knowledge of immune responses against HIV-1 and of its evolution within the host, it remains unclear why control of the virus eventually breaks down. Here, we present a new theoretical framework for the infection dynamics of HIV-1 that combines antibody and CD8(+)...

Полное описание

Библиографические подробности
Главные авторы:	Wikramaratna, P, Lourenço, J, Klenerman, P, Pybus, O, Gupta, S
Формат:	Journal article
Язык:	English
Опубликовано:	Royal Society 2015
Предметы:	Evolution Health and disease and epidemiology Immunology Computational biology Systems biology Theoretical biology

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