Immunogenicity and protective efficacy of mycobacterial DNA vaccines incorporating plasmid-encoded cytokines against Mycobacterium bovis.

DNA-based vaccines, alone or in combination with other sub-unit vaccination regimes, represent an alternative to live mycobacterial vaccines for protective immunization against tuberculosis. Here, we have used a murine immunization or Mycobacterium bovis aerosol challenge model to assess the immunog...

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Bibliographic Details
Main Authors: Young, S, Slobbe, L, Peacey, M, Gilbert, S, Buddle, B, de Lisle, G, Buchan, G
Format: Journal article
Language:English
Published: 2010