Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

Polygenic risk scores (PRSs) have been widely explored in precision medicine. However, few studies have thoroughly investigated their best practices in global populations across different diseases. We here utilized data from Global Biobank Meta-analysis Initiative (GBMI) to explore methodological co...

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Egile Nagusiak: Wang, Y, Namba, S, Lopera, E, Kerminen, S, Tsuo, K, Läll, K, Kanai, M, Zhou, W, Wu, K-H, Favé, M-J, Bhatta, L, Awadalla, P, Brumpton, B, Deelen, P, Hveem, K, Lo Faro, V, Mägi, R, Murakami, Y, Sanna, S, Smoller, JW, Uzunovic, J, Wolford, BN, Willer, C, Gamazon, ER, Cox, NJ, Surakka, I, Okada, Y, Martin, AR, Hirbo, J, Millwood, IY
Beste egile batzuk: Global Biobank Meta-analysis Initiative
Formatua: Journal article
Hizkuntza:English
Argitaratua: Cell Press 2023

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