The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production.
NF-ATc1 is a member of a family of genes that encodes the cytoplasmic component of the nuclear factor of activated T cells (NF-AT). In activated T cells, nuclear NF-AT binds to the promoter regions of multiple cytokine genes and induces their transcription. The role of NF-ATc1 was investigated in re...
主要な著者: | , , , , , , , , , , , , , |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
1998
|