The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production.

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production.

NF-ATc1 is a member of a family of genes that encodes the cytoplasmic component of the nuclear factor of activated T cells (NF-AT). In activated T cells, nuclear NF-AT binds to the promoter regions of multiple cytokine genes and induces their transcription. The role of NF-ATc1 was investigated in re...

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Hlavní autoři: Yoshida, H, Nishina, H, Takimoto, H, Marengère, L, Wakeham, A, Bouchard, D, Kong, Y, Ohteki, T, Shahinian, A, Bachmann, M, Ohashi, P, Penninger, J, Crabtree, G, Mak, T
Médium: Journal article
Jazyk:English
Vydáno: 1998

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