Investigating the role of iASPP in normal prostate development and prostate tumourigenesis
<p>Loss of TP63 expression in the prostate epithelium is a hallmark of invasive prostate cancer. An inability of prostate epithelial cells to undergo apoptosis, a process regulated by both TP63 and TP53, is a feature of their malignant transformation. <em>p53</em> mutations in pros...
| Main Authors: | , |
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| Format: | Thesis |
| Language: | English |
| Published: |
2013
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| Subjects: |