Targeting group II PAKs in cancer and metastasis.
The p21 activated kinases (PAKs) play an essential role in cell signaling and control a variety of cellular functions including cell motility, survival, angiogenesis and mitosis. PAKs are important regulators in growth factor signaling, cytoskeletal reorganization and growth factor-mediated cell mig...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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| Subjects: |