Targeting group II PAKs in cancer and metastasis.
The p21 activated kinases (PAKs) play an essential role in cell signaling and control a variety of cellular functions including cell motility, survival, angiogenesis and mitosis. PAKs are important regulators in growth factor signaling, cytoskeletal reorganization and growth factor-mediated cell mig...
Main Authors: | Eswaran, J, Soundararajan, M, Knapp, S |
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格式: | Journal article |
语言: | English |
出版: |
2009
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主题: |
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