Targeting group II PAKs in cancer and metastasis.

The p21 activated kinases (PAKs) play an essential role in cell signaling and control a variety of cellular functions including cell motility, survival, angiogenesis and mitosis. PAKs are important regulators in growth factor signaling, cytoskeletal reorganization and growth factor-mediated cell mig...

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Hlavní autoři: Eswaran, J, Soundararajan, M, Knapp, S
Médium: Journal article
Jazyk:English
Vydáno: 2009
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