The role of acidity in solid tumour growth and invasion.

Acidic pH is a common characteristic of human tumours. It has a significant impact on tumour progression and response to therapies. In this paper, we develop a simple model of three-dimensional tumour growth to examine the role of acidosis in the interaction between normal and tumour cell population...

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Bibliographic Details
Main Authors: Smallbone, K, Gavaghan, D, Gatenby, R, Maini, P
Format: Journal article
Language:English
Published: 2005