Examining the role of Rac1 in tumor angiogenesis and growth: a clinically relevant RNAi-mediated approach.

Angiogenesis, the sprouting of new blood vessels from the pre-existing vasculature, is a well established target in anti-cancer therapy. It is thought that the Rho GTPase Rac1 is required during vascular endothelial growth factor (VEGF)-mediated angiogenesis. In the present study, we have used a cli...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Vader, P, van der Meel, R, Symons, M, Fens, M, Pieters, E, Wilschut, K, Storm, G, Jarzabek, M, Gallagher, WM, Schiffelers, R, Byrne, A
التنسيق: Journal article
اللغة:English
منشور في: 2011