Vaccine route, dose and type of delivery vector determine patterns of primary CD8+ T cell responses.

Vaccine route, dose and type of delivery vector determine patterns of primary CD8+ T cell responses.

The dynamics of primary CD8+ T cell responses following administration of modified virus Ankara (MVA)- and DNA-vectored vaccines was investigated in a mouse model. To overcome the low frequency of naive antigen-specific precursors and follow the early expansion events, naive CFSE-labelled T cell rec...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Estcourt, M, Létourneau, S, Mcmichael, A, Hanke, T
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2005

समान संसाधन

Altered primary CD8+ T cell response to a modified virus Ankara(MVA)-vectored vaccine in the absence of CD4+ T cell help.
द्वारा: Estcourt, M, और अन्य
प्रकाशित: (2005)

The quest for an AIDS vaccine: is the CD8+ T-cell approach feasible?
द्वारा: McMichael, A, और अन्य
प्रकाशित: (2002)

DNA vaccines against human immunodeficiency virus type 1.
द्वारा: Estcourt, M, और अन्य
प्रकाशित: (2004)

Is a human CD8 T-cell vaccine possible, and if so, what would it take? Could a CD8+ T-cell vaccine prevent persistent HIV infection?
द्वारा: McMichael, A
प्रकाशित: (2017)

Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges.
द्वारा: Im, E, और अन्य
प्रकाशित: (2011)

Induction of human immunodeficiency virus type 1-specific T cells by a bluetongue virus tubule-vectored vaccine prime-recombinant modified virus Ankara boost regimen.
द्वारा: Larke, N, और अन्य
प्रकाशित: (2005)

CD8 T Cell Vaccines and a Cytomegalovirus-Based Vector Approach
द्वारा: Marko Šustić, और अन्य
प्रकाशित: (2021-10-01)

Novel Administration Routes, Delivery Vectors, and Application of Vaccines Based on Biotechnologies: A Review
द्वारा: Chung-I Rai, और अन्य
प्रकाशित: (2024-09-01)

Induction of long-lasting multi-specific CD8+ T cells by a four-component DNA-MVA/HIVA-RENTA candidate HIV-1 vaccine in rhesus macaques.
द्वारा: Im, E, और अन्य
प्रकाशित: (2006)

Blocking development of a CD8+ T cell response by targeting lymphatic recruitment of APC.
द्वारा: Teoh, D, और अन्य
प्रकाशित: (2009)

Effect of epitope variant co-delivery on the depth of CD8 T cell responses induced by HIV-1 conserved mosaic vaccines
द्वारा: Edmund G. Wee, और अन्य
प्रकाशित: (2021-06-01)

IL-10 Receptor Blockade Enhances CD4 and CD8 T Cell Responses to a Simian Adenovirus-Vectored HIV-1 Vaccine, ChAdV63.HIVconsv
द्वारा: Clutton, G, और अन्य
प्रकाशित: (2013)

Is an HIV vaccine possible?
द्वारा: Mcmichael, A, और अन्य
प्रकाशित: (1999)

HIV vaccines 1983-2003.
द्वारा: Mcmichael, A, और अन्य
प्रकाशित: (2003)

Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges.
द्वारा: Eung-Jun Im, और अन्य
प्रकाशित: (2011-05-01)

Development of a Universal T Cell Vaccine
द्वारा: Rosario, M, और अन्य
प्रकाशित: (2008)

Delivery Routes for COVID-19 Vaccines
द्वारा: Jang Hyun Park, और अन्य
प्रकाशित: (2021-05-01)

Exploitation of Unconventional CD8 T-Cell Responses Induced by Engineered Cytomegaloviruses for the Development of an HIV-1 Vaccine
द्वारा: Joseph Bruton, और अन्य
प्रकाशित: (2025-01-01)

Immunologic Dose-Response to Adenovirus-Vectored Vaccines in Animals and Humans: A Systematic Review of Dose-Response Studies of Replication Incompetent Adenoviral Vaccine Vectors when Given via an Intramuscular or Subcutaneous Route
द्वारा: Sara Afrough, और अन्य
प्रकाशित: (2020-03-01)

Clinical experience with plasmid DNA- and modified vaccinia virus Ankara-vectored human immunodeficiency virus type 1 clade A vaccine focusing on T-cell induction.
द्वारा: Hanke, T, और अन्य
प्रकाशित: (2007)

Vector delivery-dependant effect of human tissue plasminogen activator signal peptide on vaccine induction of T cells
द्वारा: Hanke, T, और अन्य
प्रकाशित: (2016)

Virosome: A vector in vaccine delivery
द्वारा: Karpe Shubham, और अन्य
प्रकाशित: (2024-01-01)

CD8(+) T-cell selection, function, and death in the primary immune response in vivo.
द्वारा: Callan, M, और अन्य
प्रकाशित: (2000)

Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: implications for their use as vaccines.
द्वारा: Tatsis, N, और अन्य
प्रकाशित: (2007)

Revisiting CD8 T-cell ‘Memory Inflation’: New Insights with Implications for Cytomegaloviruses as Vaccine Vectors
द्वारा: Rafaela Holtappels, और अन्य
प्रकाशित: (2020-07-01)

Biodistribution and persistence of an MVA-vectored candidate HIV vaccine in SIV-infected rhesus macaques and SCID mice.
द्वारा: Hanke, T, और अन्य
प्रकाशित: (2005)

An AAV vector-mediated gene delivery approach facilitates reconstitution of functional human CD8+ T cells in mice.
द्वारा: Jing Huang, और अन्य
प्रकाशित: (2014-01-01)

MVA as a vector for vaccines against HIV-1.
द्वारा: Im, E, और अन्य
प्रकाशित: (2004)

Quantitation of antigen-specific CD8+ T-cell responses.
द्वारा: Ogg, G, और अन्य
प्रकाशित: (1999)

Differentiation and activation antigens on CD8 T cells
द्वारा: Mongkolsapaya, J, और अन्य
प्रकाशित: (1996)

Adenoviral-vectored neoantigen vaccine augments hyperexpanded CD8+ T cell control of tumor challenge in mice
द्वारा: David Li, और अन्य
प्रकाशित: (2024-12-01)

Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya.
द्वारा: Hanke, T, और अन्य
प्रकाशित: (2000)

Aerosolized adenovirus-vectored vaccine as an alternative vaccine delivery method
द्वारा: Roy Chad J, और अन्य
प्रकाशित: (2011-11-01)

The Influence of Delivery Vectors on HIV Vaccine Efficacy
द्वारा: Beatrice Omusiro Ondondo
प्रकाशित: (2014-08-01)

An analysis of the events involved in the differentiation of naive CD8+T cells during a primary immune response in vivo
द्वारा: Chiu, C, और अन्य
प्रकाशित: (2005)

Design and tests of an HIV vaccine.
द्वारा: McMichael, A, और अन्य
प्रकाशित: (2002)

Evidence for the persistence of monoclonal expansions of CD8+ T cells following primary simian immunodeficiency virus infection.
द्वारा: Wilson, J, और अन्य
प्रकाशित: (1998)

Control of HIV-1 by CD8+T cells specific for epitopes of conserved mosaic vaccine immunogens
द्वारा: Murakoshi, H, और अन्य
प्रकाशित: (2018)

Design and pre-clinical evaluation of a universal HIV-1 vaccine.
द्वारा: Létourneau, S, और अन्य
प्रकाशित: (2007)

Early acquisition of cytolytic function and transcriptional changes in a primary CD8+ T-cell response in vivo.
द्वारा: Chiu, C, और अन्य
प्रकाशित: (2007)