Influence of the HLA-DRB1 locus on susceptibility and severity in rheumatoid arthritis.

Influence of the HLA-DRB1 locus on susceptibility and severity in rheumatoid arthritis.

We examined HLA-DR genotype risk in 288 patients with rheumatoid arthritis who were carefully categorized for disease severity. Five hundred ethnically-matched bone-marrow donors were controls. A hierarchy of positive allelic associations was noted with DRB1*0401 (p < 10(-38), *0404,8 (p &...

書誌詳細
主要な著者:	Hall, F, Weeks, D, Camilleri, J, Williams, L, Amos, N, Darke, C, Gibson, K, Pile, K, Wordsworth, B, Jessop, J
フォーマット:	Journal article
言語:	English
出版事項:	1996

類似資料

HLA-Dw4 association with rheumatoid arthritis: comment on the article by Nelson et al.
著者:: Pile, K, 等
出版事項: (1995)

HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region.
著者:: Wordsworth, B, 等
出版事項: (1989)

Does the locus on chromosome 11 implicated in susceptibility to HLA-DR4 dependent type I diabetes mellitus also affect susceptibility to rheumatoid arthritis?
著者:: Pile, K, 等
出版事項: (1992)

HLA heterozygosity contributes to susceptibility to rheumatoid arthritis.
著者:: Wordsworth, B, 等
出版事項: (1992)

HLA-DR HETEROZYGOSITY CONTRIBUTES SUSCEPTIBILITY TO SEVERE RHEUMATOID-ARTHRITIS
著者:: Pile, K, 等
出版事項: (1992)

CLINICAL IMPORTANCE OF DETERMINATION OF HLA-DRB1 LOCUS GENES IN RHEUMATOID ARTHRITIS
著者:: V. Guseva, 等
出版事項: (2019-05-01)

Identification of a Non-HLA-DRB1 genetic effect in a 100kb interval in the MHC class III region in rheumatoid arthritis.
著者:: Harney, S, 等
出版事項: (2003)

A GENE INTERACTIVE WITH HLA-DR4 IN SUSCEPTIBILITY TO TYPE-I DIABETES IS NOT INVOLVED IN RHEUMATOID-ARTHRITIS (RA)
著者:: Pile, K, 等
出版事項: (1992)

HLA-DRB1 alleles in patients with rheumatoid arthritis
著者:: L A Taukumova, 等
出版事項: (2004-08-01)

A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population.
著者:: Mackie, S, 等
出版事項: (2012)

HLA class II antigens in susceptibility to rheumatoid arthritis.
著者:: Wordsworth, B
出版事項: (1991)

Association of HLA-DRB1*13 with susceptibility to uveitis in juvenile idiopathic arthritis in two independent data sets.
著者:: Zeggini, E, 等
出版事項: (2006)

HLA-DR4 subtyping by single-strand polymorphism analysis.
著者:: Pile, K, 等
出版事項: (1993)

HLA-DRB1 influence on anti-TNF treatment in British Caucasian rheumatoid arthritis patients
著者:: Harrison, P, 等
出版事項: (2006)

Association of HLA-DRB1 locus with treatment response to abatacept or TNF inhibitors in patients with seropositive rheumatoid arthritis
著者:: Soojin Cha, 等
出版事項: (2024-03-01)

The HLA class II component of susceptibility to rheumatoid arthritis.
著者:: Wordsworth, B, 等
出版事項: (1992)

CONFIRMATION OF ASSOCIATION OF HLA-DRB1*13 WITH UVEITIS IN JUVENILE IDIOPATHIC ARTHRITIS
著者:: Zeggini, E, 等
出版事項: (2004)

Hematological parameters in patients with rheumatoid arthritis and gene variants HLA-DRB1*04 and HLA-DRB1*03
著者:: Biljana Klimenta, 等
出版事項: (2020-06-01)

MHC class III genes in rheumatoid arthritis and the differential association of HLA-DRB1 alleles with disease
著者:: Harney, S, 等
出版事項: (2005)

The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis.
著者:: Brown, M, 等
出版事項: (1998)

Association of mycoplasma pneumoniae and (rs9271366) HLA-DRB1gene polymorphism with the immune susceptibility to rheumatoid arthritis
著者:: Wael Rasheed Obaead Alfatlawi, 等
出版事項: (2023-01-01)

A novel HLA-DR4 allele (DRB1*0414) in a patient with myasthenia gravis.
著者:: Pile, K, 等
出版事項: (1992)

HLA-DR antigens and rheumatoid arthritis in black South Africans: a study of ethnic groups.
著者:: Pile, K, 等
出版事項: (1992)

The effect of HLA-DR on susceptibility to rheumatoid arthritis is influenced by the associated lymphotoxin alpha-tumor necrosis factor haplotype.
著者:: Newton, J, 等
出版事項: (2003)

Challenges in mapping non-HLA-DRB1 major histocompatibility genes in rheumatoid arthritis: comment on the article by Vignal et al.
著者:: Brown, M, 等
出版事項: (2009)

Study the association of Mycoplasma pneumoniae and (rs35445101) HLA-DRB1gene polymorphism with the immune susceptibility to rheumatoid arthritis
著者:: Wael Rasheed Obaead Alfatlawi, 等
出版事項: (2023-01-01)

OLIGONUCLEOTIDE DNA TYPING ANALYSIS OF THE HLA DRB3 LOCUS IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS (PSC)
著者:: Mehal, W, 等
出版事項: (1991)

THE HLA CLASS II ASSOCIATIONS OF RHEUMATOID-ARTHRITIS CONFER SEVERITY NOT SUSCEPTIBILITY
著者:: Gough, A, 等
出版事項: (1992)

HLA-DR/DQ haplotype in rheumatoid arthritis: novel allelic associations in UK Caucasians.
著者:: Milicic, A, 等
出版事項: (2002)

Dynamics of circulating follicular helper T cell subsets and follicular regulatory T cells in rheumatoid arthritis patients according to HLA-DRB1 locus
著者:: Paola V. Ferrero, 等
出版事項: (2022-12-01)

Frequency of HLA-DRB1 alleles in rheumatoid arthritis patients in Zahedan, southeast Iran
著者:: Sandoughi Mahnaz, 等
出版事項: (2011-01-01)

HLA-DP LOCUS IN ATOPIC IGE RESPONSES
著者:: Young, R, 等
出版事項: (1993)

Linkage analysis of potential rheumatoid arthritis non-HLA susceptibility loci.
著者:: MacKay, K, 等
出版事項: (2000)

RHEUMATOID-ARTHRITIS IS NOT PRIMARILY ASSOCIATED WITH A VARIANT OF THE TAP-2 GENE
著者:: Wordsworth, B, 等
出版事項: (1993)

Susceptibility to rheumatoid arthritis is not associated with a single common allele of the type 2 collagen gene (COL2A1)
著者:: Pile, K, 等
出版事項: (1993)

Large multifunctional protease 2 genes in rheumatoid arthritis.
著者:: Pile, K, 等
出版事項: (1994)

A majority of Brazilian patients with rheumatoid arthritis HLA-DRB1 alleles carry both the HLA-DRB1 shared epitope and anti-citrunillated peptide antibodies
著者:: P. Louzada-Júnior, 等
出版事項: (2008-06-01)

Polygenic susceptibility in rheumatoid arthritis.
著者:: Wordsworth, B, 等
出版事項: (1991)

Associação do alelo HLA-DRB1 com suscetibilidade a artrite reumatoide e gravidade da doença na Síria HLA-DRB1 allele association with rheumatoid arthritis susceptibility and severity in Syria
著者:: Jamil Mourad, 等
出版事項: (2013-02-01)

Genetic modelling in rheumatoid arthritis: cat walk or tight rope?
著者:: Wordsworth, P, 等
出版事項: (1994)