Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes

Because enriched environment (EE) and exercise increase and aging decreases immune response, we hypothesized that environmental enrichment and aging will, respectively, delay and increase prion disease progression. Mice dorsal striatum received bilateral stereotaxic intracerebral injections of norma...

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Bibliographic Details
Main Authors: Bento-Torres, J, Sobral, L, Reis, R, De Oliveira, R, Anthony, D, Vasconcelos, P, Picanço Diniz, C
Format: Journal article
Published: Hindawi Publishing Corporation 2017