A new method to sort differentiating osteoclasts into defined homogeneous subgroups

Osteoclasts regulate skeletal development but also drive pathological osteolysis, making them prime therapeutic targets. Osteoclast research is limited by the heterogeneity of osteoclast populations generated in vitro, where the mixture of undifferentiated monocytes, binuclear pre-osteoclasts and mu...

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Bibliographic Details
Main Authors: Hulley, PA, Knowles, HJ
Format: Journal article
Language:English
Published: MDPI 2022