Controlling curvature in a family of oligoamide alpha-helix mimetics.
(Figure Presented) Catching up with the curve! The natural curvature found in a majority of a helices has been mimicked in small synthetic oligoamide scaffolds. Differences in hydrogen-bonding patterns in these scaffolds lead to mimetics with varying degrees of curvature in the backbone. This adds a...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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