Controlling curvature in a family of oligoamide alpha-helix mimetics.
(Figure Presented) Catching up with the curve! The natural curvature found in a majority of a helices has been mimicked in small synthetic oligoamide scaffolds. Differences in hydrogen-bonding patterns in these scaffolds lead to mimetics with varying degrees of curvature in the backbone. This adds a...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2008
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| _version_ | 1826267975008649216 |
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| author | Saraogi, I Incarvito, C Hamilton, A |
| author_facet | Saraogi, I Incarvito, C Hamilton, A |
| author_sort | Saraogi, I |
| collection | OXFORD |
| description | (Figure Presented) Catching up with the curve! The natural curvature found in a majority of a helices has been mimicked in small synthetic oligoamide scaffolds. Differences in hydrogen-bonding patterns in these scaffolds lead to mimetics with varying degrees of curvature in the backbone. This adds another parameter to the structural and functional mimicry of a helices. © 2008 Wiley-VCH Verlag GmbH and Co. KGaA. |
| first_indexed | 2024-03-06T21:02:31Z |
| format | Journal article |
| id | oxford-uuid:3b58d7c0-0765-404c-a16a-a1cdc3faa6de |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:02:31Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:3b58d7c0-0765-404c-a16a-a1cdc3faa6de2022-03-26T14:07:06ZControlling curvature in a family of oligoamide alpha-helix mimetics.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3b58d7c0-0765-404c-a16a-a1cdc3faa6deEnglishSymplectic Elements at Oxford2008Saraogi, IIncarvito, CHamilton, A(Figure Presented) Catching up with the curve! The natural curvature found in a majority of a helices has been mimicked in small synthetic oligoamide scaffolds. Differences in hydrogen-bonding patterns in these scaffolds lead to mimetics with varying degrees of curvature in the backbone. This adds another parameter to the structural and functional mimicry of a helices. © 2008 Wiley-VCH Verlag GmbH and Co. KGaA. |
| spellingShingle | Saraogi, I Incarvito, C Hamilton, A Controlling curvature in a family of oligoamide alpha-helix mimetics. |
| title | Controlling curvature in a family of oligoamide alpha-helix mimetics. |
| title_full | Controlling curvature in a family of oligoamide alpha-helix mimetics. |
| title_fullStr | Controlling curvature in a family of oligoamide alpha-helix mimetics. |
| title_full_unstemmed | Controlling curvature in a family of oligoamide alpha-helix mimetics. |
| title_short | Controlling curvature in a family of oligoamide alpha-helix mimetics. |
| title_sort | controlling curvature in a family of oligoamide alpha helix mimetics |
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