A CD45 polymorphism associated with abnormal splicing is absent in African populations.

The CD45 antigen is essential for normal antigen receptor-mediated signalling in lymphocytes, and different patterns of splicing of CD45 are associated with distinct functions in lymphocytes. Abnormal CD45 splicing has been recognized in humans, caused by a C77G transversion in the gene encoding CD4...

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Bibliographic Details
Main Authors:	Tchilian, E, Dawes, R, Ramaley, P, Whitworth, J, Yuldasheva, N, Wells, R, Watera, C, French, N, Gilks, C, Kunachiwa, W, Ruzibakiev, R, Leetrakool, N, Carrington, C, Ramdath, D, Gotch, F, Stephens, H, Hill, A, Beverley, P
Format:	Journal article
Language:	English
Published:	2002

A CD45 polymorphism associated with abnormal splicing is absent in African populations.

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