A CD45 polymorphism associated with abnormal splicing is absent in African populations.
The CD45 antigen is essential for normal antigen receptor-mediated signalling in lymphocytes, and different patterns of splicing of CD45 are associated with distinct functions in lymphocytes. Abnormal CD45 splicing has been recognized in humans, caused by a C77G transversion in the gene encoding CD4...
Main Authors: | , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado: |
2002
|
Search Result 1
A CD45 polymorphism associated with abnormal splicing is absent in African populations
Publicado 2002
Journal article