A CD45 polymorphism associated with abnormal splicing is absent in African populations.

The CD45 antigen is essential for normal antigen receptor-mediated signalling in lymphocytes, and different patterns of splicing of CD45 are associated with distinct functions in lymphocytes. Abnormal CD45 splicing has been recognized in humans, caused by a C77G transversion in the gene encoding CD4...

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Hlavní autoři:	Tchilian, E, Dawes, R, Ramaley, P, Whitworth, J, Yuldasheva, N, Wells, R, Watera, C, French, N, Gilks, C, Kunachiwa, W, Ruzibakiev, R, Leetrakool, N, Carrington, C, Ramdath, D, Gotch, F, Stephens, H, Hill, A, Beverley, P
Médium:	Journal article
Jazyk:	English
Vydáno:	2002

A CD45 polymorphism associated with abnormal splicing is absent in African populations Autor Tchilian, E, Dawes, R, Ramaley, P, Whitworth, J, Yuldasheva, N, Wells, R, Watera, C, French, N, Gilks, C, Kunachiwa, W, Ruzibakiev, R, Leetrakool, N, Carrington, C, Ramdath, D, Gotch, F, Stephens, H, Hill, A, Beverley, P

Vydáno 2002

Journal article

A CD45 polymorphism associated with abnormal splicing is absent in African populations.

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