Platelet 5-HT receptor binding during depressive illness and tricyclic antidepressant treatment.

5-Hydroxytryptamine (5-HT) receptor binding was determined in intact human platelets using 125I-iodolysergic acid diethylamide (125I-iodoLSD). The assay revealed that platelets possess a single population of specific binding sites for 125I-iodoLSD which have a high affinity for the 5-HT2 receptor an...

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Bibliographic Details
Main Authors: Cowen, P, Charig, E, Fraser, S, Elliott, J
Format: Journal article
Language:English
Published: 1987