Therapeutic antibodies elicited by immunization against TNF-alpha.

Tumor necrosis factor-alpha (TNF-alpha) is critically involved in the pathogenesis of several chronic inflammatory diseases. Monoclonal antibodies against TNF-alpha are currently used for the treatment of rheumatoid arthritis and Crohn's disease. This report describes a simple and effective met...

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Bibliographic Details
Main Authors: Dalum, I, Butler, D, Jensen, MR, Hindersson, P, Steinaa, L, Waterston, A, Grell, SN, Feldmann, M, Elsner, H, Mouritsen, S
Format: Journal article
Language:English
Published: 1999