Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation.

Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation.

Mutations in the human methyl-CpG-binding protein gene MECP2 cause the neurological disorder Rett syndrome and some cases of X-linked mental retardation (XLMR). We report that MeCP2 interacts with ATRX, a SWI2/SNF2 DNA helicase/ATPase that is mutated in ATRX syndrome (alpha-thalassemia/mental retard...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Nan, X, Hou, J, Maclean, A, Nasir, J, Lafuente, M, Shu, X, Kriaucionis, S, Bird, A
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2007

Míreanna comhchosúla

Mutations in the chromatin-associated protein ATRX.
de réir: Gibbons, R, et al.
Foilsithe / Cruthaithe: (2008)

A nonsense mutation of the ATRX gene causing mild mental retardation and epilepsy.
de réir: Guerrini, R, et al.
Foilsithe / Cruthaithe: (2000)

The major form of MeCP2 has a novel N-terminus generated by alternative splicing.
de réir: Kriaucionis, S, et al.
Foilsithe / Cruthaithe: (2004)

Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX.
de réir: Argentaro, A, et al.
Foilsithe / Cruthaithe: (2007)

Recognition of the nucleosome by the chromatin remodeler atrx
de réir: Feng, Xiaoyu
Foilsithe / Cruthaithe: (2017)

Disruption of ATRX in mouse by conditional knockout.
de réir: Gibbons, R, et al.
Foilsithe / Cruthaithe: (2002)

Role of the chromatin remodeler ATRX in the regulation of gene expression
de réir: Truch, J
Foilsithe / Cruthaithe: (2018)

A critique of the hypothesis that CA repeats are primary targets of neuronal MeCP2
de réir: Chhatbar, K, et al.
Foilsithe / Cruthaithe: (2022)

The role of chromatin remodeller ATRX in gene expression
de réir: Shen, Y
Foilsithe / Cruthaithe: (2022)

Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function
de réir: Wenqing Ren, et al.
Foilsithe / Cruthaithe: (2020-05-01)

ATRX contributes to MeCP2-mediated pericentric heterochromatin organization during neural differentiation
de réir: Marano, D, et al.
Foilsithe / Cruthaithe: (2019)

Identification of acquired somatic mutations in the chromatin remodelling factor ATRX in the a thalassaemia myelodysplasia syndrome (ATMDS)
de réir: Gibbons, R, et al.
Foilsithe / Cruthaithe: (2003)

Identification of acquired somatic mutations in the chromatin remodelling factor ATRX in the alpha thalassemia myelodysplasia syndrome (ATMDS).
de réir: Gibbons, R, et al.
Foilsithe / Cruthaithe: (2003)

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.
de réir: Mellén, M, et al.
Foilsithe / Cruthaithe: (2012)

MeCP2 and Chromatin Compartmentalization
de réir: Annika Schmidt, et al.
Foilsithe / Cruthaithe: (2020-04-01)

The chromatin remodelling factor dATRX is involved in heterochromatin formation.
de réir: Andrew R Bassett, et al.
Foilsithe / Cruthaithe: (2008-05-01)

The chromatin remodeller ATRX: A repeat offender in human disease
de réir: Clynes, D, et al.
Foilsithe / Cruthaithe: (2013)

The chromatin remodeller ATRX: a repeat offender in human disease.
de réir: Clynes, D, et al.
Foilsithe / Cruthaithe: (2013)

Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the alpha-thalassemia myelodysplasia syndrome (ATMDS).
de réir: Gibbons, R, et al.
Foilsithe / Cruthaithe: (2003)

The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis.
de réir: Bérubé, N, et al.
Foilsithe / Cruthaithe: (2005)

A nonsense mutation of the ATRX gene causing mild, moderate and profound mental retardation in members of a single family.
de réir: Gibbons, R, et al.
Foilsithe / Cruthaithe: (1999)

The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats
de réir: Nguyen, D, et al.
Foilsithe / Cruthaithe: (2017)

How does the chromatin remodeler ATRX identify its targets in the genome?
de réir: Nguyen, DTT
Foilsithe / Cruthaithe: (2014)

MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex.
de réir: Klose, R, et al.
Foilsithe / Cruthaithe: (2004)

X-linked alpha thalassaemia/mental retardation syndrome: a case with gonadal dysgenesis, caused by a novel mutation in ATRX gene.
de réir: Jezela-Stanek, A, et al.
Foilsithe / Cruthaithe: (2009)

MYCN amplification and ATRX mutations are incompatible in neuroblastoma
de réir: Maged Zeineldin, et al.
Foilsithe / Cruthaithe: (2020-02-01)

Identification of mutations in ATRX by RNase mismatch cleavage.
de réir: Gibbons, R, et al.
Foilsithe / Cruthaithe: (1997)

ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress
de réir: Joseph M Cabral, et al.
Foilsithe / Cruthaithe: (2018-11-01)

DAXX-ATRX regulation of p53 chromatin binding and DNA damage response
de réir: Nitish Gulve, et al.
Foilsithe / Cruthaithe: (2022-08-01)

Choroidal melanoma with synchronous Fuchs’ adenoma and novel ATRX mutation
de réir: Elli Harford, et al.
Foilsithe / Cruthaithe: (2022-04-01)

Mutant ATRX: pathogenesis of ATRX syndrome and cancer
de réir: Kejia Yuan, et al.
Foilsithe / Cruthaithe: (2024-10-01)

Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart
de réir: Harikrishnan K.N., et al.
Foilsithe / Cruthaithe: (2019-07-01)

Variant ATRX syndrome with dysfunction of ATRX and MAGT1 genes.
de réir: Qiao, Y, et al.
Foilsithe / Cruthaithe: (2014)

MECP2 Mutations and Rett Syndrome Phenotypes
de réir: J Gordon Millichap
Foilsithe / Cruthaithe: (2000-05-01)

Neurodevelopmental Disorders Caused by Defective Chromatin Remodeling: Phenotypic Complexity Is Highlighted by a Review of ATRX Function
de réir: Sara Timpano, et al.
Foilsithe / Cruthaithe: (2020-08-01)

Functional significance of mutations in the Snf2 domain of ATRX.
de réir: Mitson, M, et al.
Foilsithe / Cruthaithe: (2011)

Alternative lengthening of telomeres is not synonymous with mutations in ATRX/DAXX
de réir: Alexandre de Nonneville, et al.
Foilsithe / Cruthaithe: (2021-03-01)

Circadian cycle-dependent MeCP2 and brain chromatin changes.
de réir: Alexia Martínez de Paz, et al.
Foilsithe / Cruthaithe: (2015-01-01)

Sequential chromatin immunoprecipitation to detect SUMOylated MeCP2 in neurons
de réir: Tao Wu, et al.
Foilsithe / Cruthaithe: (2016-03-01)

alpha-thalassaemia, X-linked mental retardation syndrome protein, ATRX, interacts with ribosomal genes.
de réir: Law, M, et al.
Foilsithe / Cruthaithe: (2003)