Chiral relay effects influence the facial selectivity of N-alkylated 5-phenylmorpholin-2-one enolates

Alkylation studies on the enolate of N-methyl morpholinone 7 clearly reveal that the observed cis-selectivity is consistent with a chiral relay system operating to invert the stereochemical information of the auxiliary's C5 stereogenic centre.

Bibliographic Details
Main Authors: Bull, S, Davies, S, Fox, D, Sellers, T
Format: Journal article
Language:English
Published: 1998