Kinetic and mechanistic requirements for helping CD8 T cells.

The requirements for the generation of fully competent long-lived memory CD8 T cells and in particular the role and the mechanisms of help from CD4 T cells remain ill-defined. Memory CD8 T cells generated in the absence of CD4 T cell help often have an impaired recall proliferation and are thus unab...

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Bibliographic Details
Main Authors: Agnellini, P, Wiesel, M, Schwarz, K, Wolint, P, Bachmann, M, Oxenius, A
Format: Journal article
Language:English
Published: 2008