The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution.
BACKGROUND: The fungal pathogen Pneumocystis carinii causes a pneumonia which is an opportunistic infection of AIDS patients. Current therapy includes the dihydrofolate reductase (DHFR) inhibitor trimethoprim which is selective but only a relatively weak inhibitor of the enzyme for P. carinii. Deter...
Үндсэн зохиолчид: | Champness, J, Achari, A, Ballantine, S, Bryant, P, Delves, C, Stammers, D |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
1994
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Ижил төстэй зүйлс
Ижил төстэй зүйлс
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The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution.
-н: Champness, J, зэрэг
Хэвлэсэн: (1994) -
Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase.
-н: Stammers, D, зэрэг
Хэвлэсэн: (1993) -
Refolding of recombinant Pneumocystis carinii dihydrofolate reductase and characterization of the enzyme.
-н: Delves, C, зэрэг
Хэвлэсэн: (1993) -
The binding of trimethoprim to bacterial dihydrofolate reductase.
-н: Baker, D, зэрэг
Хэвлэсэн: (1981) -
Pneumocystis carinii
-н: J. M. HOPKIN
Хэвлэсэн: (1993-02-01)