Structure of the periplasmic component of a bacterial drug efflux pump.

Multidrug resistance among Gram-negative bacteria is conferred by three-component membrane pumps that expel diverse antibiotics from the cell. These efflux pumps consist of an inner membrane transporter such as the AcrB proton antiporter, an outer membrane exit duct of the TolC family, and a peripla...

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Bibliographic Details
Main Authors: Higgins, M, Bokma, E, Koronakis, E, Hughes, C, Koronakis, V
Format: Journal article
Language:English
Published: 2004