Effects of vaccinia virus anti-inflammatory protein 35K and TIMP-1 gene transfers on vein graft stenosis in rabbits.
BACKGROUND: Vein graft stenosis is a common problem after bypass surgery. Vein grafts are ideal targets for gene therapy because transduction can be made ex vivo before grafting. Since chemokines and inflammatory factors are involved in vein graft thickening, we tested a hypothesis that the vaccini...
Những tác giả chính: | Puhakka, H, Turunen, P, Gruchala, M, Bursill, C, Heikura, T, Vajanto, I, Greaves, D, Channons, K, Ylä-Herttuala, S |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2005
|
Những quyển sách tương tự
-
Adenovirus-mediated gene transfer of Lp-PLA2 reduces LDL degradation and foam cell formation in vitro
Bằng: Päivi Turunen, et al.
Được phát hành: (2004-09-01) -
A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
Bằng: Bursill, C, et al.
Được phát hành: (2005) -
Adenoviral mediated delivery of a vaccinia viral protein (35K) blocks CC-chemokine activity in vitro and in vivo and may therefore be a useful therapeutic strategy to reduce the initiation and progression of CC-chemokine induced atherosclerosis
Bằng: Bursill, C, et al.
Được phát hành: (2003) -
Rabbit atherosclerotic lesions express scavenger receptor AIII mRNA, a naturally occurring splice variant that encodes a non-functional, dominant negative form of the macrophage scavenger receptor.
Bằng: Hiltunen, T, et al.
Được phát hành: (2001) -
Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression.
Bằng: Margreet R de Vries, et al.
Được phát hành: (2012-01-01)