Novel HIV-1 clade B candidate vaccines designed for HLA-B*5101(+) patients protected mice against chimaeric ecotropic HIV-1 challenge.

Novel candidate HIV-1 vaccines have been constructed, which are tailor-designed for HLA-B*5101(+) patients infected with HIV-1 clade B. These vaccines employ novel immunogen HIVB-B*5101 derived from consensus HIV-1 clade B Gag p17 and p24 regions coupled to two Pol-derived B*5101-restricted epitopes...

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Bibliographic Details
Main Authors: Roshorm, Y, Hong, J, Kobayashi, N, Mcmichael, A, Volsky, D, Potash, M, Takiguchi, M, Hanke, T
Format: Journal article
Language:English
Published: 2009