Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension

It is well established that gene interactions influence common human diseases, but to date linkage studies have been constrained to searching for single genes across the genome. We applied a novel approach to uncover significant gene-gene interactions in a systematic two-dimensional (2D) genome-scan...

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Huvudupphovsmän: Tzenova Bell, J, Wallace, C, Dobson, R, Wiltshire, S, Mein, C, Pembroke, J, Brown, M, Clayton, D, Samani, N, Dominiczak, A, Webster, J, Lathrop, G, Connell, J, Munroe, P, Caulfield, M, Farrall, M
Materialtyp: Journal article
Språk:English
Publicerad: Oxford University Press 2006
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