Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension

Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension

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It is well established that gene interactions influence common human diseases, but to date linkage studies have been constrained to searching for single genes across the genome. We applied a novel approach to uncover significant gene-gene interactions in a systematic two-dimensional (2D) genome-scan...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Tzenova Bell, J, Wallace, C, Dobson, R, Wiltshire, S, Mein, C, Pembroke, J, Brown, M, Clayton, D, Samani, N, Dominiczak, A, Webster, J, Lathrop, G, Connell, J, Munroe, P, Caulfield, M, Farrall, M
Format:	Journal article
Sprache:	English
Veröffentlicht:	Oxford University Press 2006
Schlagworte:	Genetics (medical sciences) Cardiovascular disease Medical sciences

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