CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation

CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation

Calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) regulates cell and whole-body metabolism and supports tumorigenesis. The cellular impacts of perturbing CAMKK2 expression are, however, not yet fully characterised. By knocking down CAMKK2 levels, we have identified a number of significan...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Stewart, L, Gerner, L, Rettel, M, Stein, F, Burrows, J, Mills, IAN, Evergren, E
Formatua:	Journal article
Argitaratua:	Springer Nature 2021

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The role of CaMKK2 in Golgi-associated vesicle trafficking
nork: Kennedy, G, et al.
Argitaratua: (2023)

Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli.
nork: Gerner, L, et al.
Argitaratua: (2016)

Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli
nork: Lisa Gerner, et al.
Argitaratua: (2016-09-01)

Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2.
nork: Gerner, L, et al.
Argitaratua: (2016)

Activation of AMPK by bitter melon triterpenoids involves CaMKKβ.
nork: Tristan J Iseli, et al.
Argitaratua: (2013-01-01)

Neuronal CaMKK2 promotes immunosuppression and checkpoint blockade resistance in glioblastoma
nork: William H. Tomaszewski, et al.
Argitaratua: (2022-10-01)

Androgen Receptor-CaMKK2 Axis in Prostate Cancer and Bone Microenvironment
nork: Ushashi C. Dadwal, et al.
Argitaratua: (2018-06-01)

Retinoic Acid-Mediated Inhibition of Mouse Coronavirus Replication Is Dependent on IRF3 and CaMKK
nork: Justin H. Franco, et al.
Argitaratua: (2024-01-01)

CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle
nork: Florentina Negoita, et al.
Argitaratua: (2023-09-01)

Assembly of Peripheral Actomyosin Bundles in Epithelial Cells Is Dependent on the CaMKK2/AMPK Pathway
nork: Eeva Kaisa Rajakylä, et al.
Argitaratua: (2020-03-01)

CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer
nork: Luigi Racioppi, et al.
Argitaratua: (2019-06-01)

Microcystin leucine arginine induces human sperm damage: Involvement of the Ca2+/CaMKKβ/AMPK pathway
nork: Xing Guo, et al.
Argitaratua: (2023-05-01)

CaMKK-CaMK1a, a new post-traumatic signalling pathway induced in mouse somatosensory neurons.
nork: Lucie Elzière, et al.
Argitaratua: (2014-01-01)

TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway
nork: A. Scotto Rosato, et al.
Argitaratua: (2019-12-01)

Liraglutide alleviates high-fat diet-induced kidney injury in mice by regulating the CaMKKβ/AMPK pathway
nork: Yingli Xuan, et al.
Argitaratua: (2024-12-01)

Aberrant expression of NEDD4L disrupts mitochondrial homeostasis by downregulating CaMKKβ in diabetic kidney disease
nork: Fei Han, et al.
Argitaratua: (2024-05-01)

Myosin-18B Promotes Mechanosensitive CaMKK2-AMPK-VASP Regulation of Contractile Actin Stress Fibers
nork: Shuangshuang Zhao, et al.
Argitaratua: (2020-04-01)

The red pepper's spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ.
nork: Alicia Bort, et al.
Argitaratua: (2019-01-01)

The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways
nork: Xubo Chen, et al.
Argitaratua: (2017-08-01)

Ssp1 CaMKK: A Sensor of Actin Polarization That Controls Mitotic Commitment through Srk1 in Schizosaccharomyces pombe.
nork: Alba Gómez-Hierro, et al.
Argitaratua: (2015-01-01)

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nork: In‐Sung Song, et al.
Argitaratua: (2024-09-01)

Quercetin induces autophagy-associated death in HL-60 cells through CaMKKβ/AMPK/mTOR signal pathway
nork: Xiao Jie, et al.
Argitaratua: (2022-09-01)

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nork: Zuodong Chen, et al.
Argitaratua: (2022-03-01)

Clopidogrel Protects Endothelium by Hindering TNFα-Induced VCAM-1 Expression through CaMKKβ/AMPK/Nrf2 Pathway
nork: Huabing Yang, et al.
Argitaratua: (2016-01-01)

CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection
nork: Rishi Kumar Jaiswal, et al.
Argitaratua: (2023-11-01)

Duck enteritis virus activates CaMKKβ-AMPK to trigger autophagy in duck embryo fibroblast cells via increased cytosolic calcium
nork: Haichang Yin, et al.
Argitaratua: (2018-08-01)

TRPC5-induced autophagy promotes drug resistance in breast carcinoma via CaMKKβ/AMPKα/mTOR pathway
nork: Peng Zhang, et al.
Argitaratua: (2017-06-01)

Enhanced expression of WD repeat-containing protein 35 via CaMKK/AMPK activation in bupivacaine-treated Neuro2a cells.
nork: Lei Huang, et al.
Argitaratua: (2014-01-01)

A high-concentrate diet induces inflammatory injury via regulating Ca2+/CaMKKβ-mediated autophagy in mammary gland tissue of dairy cows
nork: Meijuan Meng, et al.
Argitaratua: (2023-05-01)

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nork: Kung-Hsien Ho, et al.
Argitaratua: (2023-02-01)

Ckip-1 3’UTR alleviates prolonged sleep deprivation induced cardiac dysfunction by activating CaMKK2/AMPK/cTNI pathway
nork: Beilei Dong, et al.
Argitaratua: (2024-06-01)

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nork: Zhifeng Huang, et al.
Argitaratua: (2024-04-01)

L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKβ-AMPK signaling pathway
nork: Juanjuan Liang, et al.
Argitaratua: (2022-04-01)

Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKKβ-Dependent AMPK Activation
nork: Chuwen Li, et al.
Argitaratua: (2018-04-01)

Baicalin Attenuates High Fat Diet-Induced Obesity and Liver Dysfunction: Dose-Response and Potential Role of CaMKKβ/AMPK/ACC Pathway
nork: Youli Xi, et al.
Argitaratua: (2015-04-01)

Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis
nork: Bingrun Liu, et al.
Argitaratua: (2019-11-01)

Cytotoxic effects of the cigarette smoke extract of heated tobacco products on human oral squamous cell carcinoma: the role of reactive oxygen species and CaMKK2
nork: Nagao Kagemichi, et al.
Argitaratua: (2024-06-01)

Electromagnetic fields ameliorate hepatic lipid accumulation and oxidative stress: potential role of CaMKKβ/AMPK/SREBP-1c and Nrf2 pathways
nork: Mingming Zhai, et al.
Argitaratua: (2023-05-01)

Expression of Concern: Enhanced Expression of WD Repeat-Containing Protein 35 via CaMKK/AMPK Activation in Bupivacaine-Treated Neuro2a Cells.
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Argitaratua: (2019-01-01)

Concurrent regulation of LKB1 and CaMKK2 in the activation of AMPK in castrate-resistant prostate cancer by a well-defined polyherbal mixture with anticancer properties
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