Quality control of protein complex assembly by a transmembrane recognition factor
The inner nuclear membrane (INM) is continuous withthe endoplasmic reticulum (ER) but harbors a distinc-tive proteome essential for nuclear functions. Inyeast, the Asi1/Asi2/Asi3 ubiquitin ligase complexsafeguards the INM proteome through the clearanceof mislocalized ER membrane proteins. How the As...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Cell Press
2019
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