Quality control of protein complex assembly by a transmembrane recognition factor

The inner nuclear membrane (INM) is continuous withthe endoplasmic reticulum (ER) but harbors a distinc-tive proteome essential for nuclear functions. Inyeast, the Asi1/Asi2/Asi3 ubiquitin ligase complexsafeguards the INM proteome through the clearanceof mislocalized ER membrane proteins. How the As...

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Bibliographic Details
Main Authors: Natarajan, N, Foresti, O, Wendrich, K, Stein, A, Carvalho, P
Format: Journal article
Language:English
Published: Cell Press 2019