Cyclin f-mediated degradation of ribonucleotide reductase m2 controls genome integrity and DNA repair

<p style="text-align:justify;"> F-box proteins are the substrate binding subunits of SCF (Skp1-Cul1-F-box protein) ubiquitin ligase complexes. Using affinity purifications and mass spectrometry, we identified RRM2 (the ribonucleotide reductase family member 2) as an interactor of th...

Full description

Bibliographic Details
Main Authors: D'Angiolella, V, Donato, V, Forrester, F, Jeong, Y, Pellacani, C, Kudo, Y, Saraf, A, Florens, L, Washburn, M, Pagano, M
Format: Journal article
Language:English
Published: Elsevier 2012