An IL-1β-driven neutrophil–stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma

Human bone marrow permanently harbors high numbers of neutrophils, and a tumor-supportive bias of these cells could significantly impact bone marrow-confined malignancies. In individuals with multiple myeloma, the bone marrow is characterized by inflammatory stromal cells with the potential to influ...

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Bibliographic Details
Main Authors: de Jong, MME, Fokkema, C, Papazian, N, Czeti, Á, Appelman, MK, Vermeulen, M, van Heusden, T, Hoogenboezem, RM, van Beek, G, Tahri, S, Sanders, MA, van de Woestijne, PC, Gay, F, Moreau, P, Büttner-Herold, M, Bruns, H, van Duin, M, Broijl, A, Sonneveld, P, Cupedo, T
Format: Journal article
Language:English
Published: Springer Nature 2024