High-performance cation-exchange chromatography and pulsed amperometric detection for the separation, detection, and quantitation of N-alkylated imino sugars in biological samples.
The use of imino sugars for the potential treatment of lysosomal glycolipid storage diseases and hepatitis virus infections requires accurate, quantitative measurement of these compounds in biological samples. We demonstrate here the versatility of cation-exchange chromatography and pulsed amperomet...
المؤلفون الرئيسيون: | Mellor, H, Adam, A, Platt, F, Dwek, R, Butters, T |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2000
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مواد مشابهة
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Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation.
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