Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area.
Many adhesion receptors have high three-dimensional dissociation constants (Kd) for counter-receptors compared to the KdS of receptors for soluble extracellular ligands such as cytokines and hormones. Interaction of the T lymphocyte adhesion receptor CD2 with its counter-receptor, LFA-3, has a high...
主要な著者: | Dustin, M, Ferguson, L, Chan, P, Springer, T, Golan, D |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
1996
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