TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen

For the protozoan parasite Leishmania, completion of its life cycle requires sequential adaptation of cellular physiology and nutrient scavenging mechanisms to the different environments of a sand fly alimentary tract and the acidic mammalian host cell phagolysosome. Transmembrane transporters are t...

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Bibliographic Details
Main Authors: Albuquerque-Wendt, A, McCoy, C, Neish, R, Dobramysl, U, Alagöz, Ç, Beneke, T, Cowley, SA, Crouch, K, Wheeler, RJ, Mottram, JC, Gluenz, E
Format: Journal article
Language:English
Published: Nature Research 2025