Ophiobolin A, a sesterpenoid fungal phytotoxin, displays different mechanisms of cell death in mammalian cells depending upon the cancer cell origin

Herein we have undertaken a systematic analysis of the effects of the fungal derivative ophiobolin A (OphA) on eight cancer cell lines from different tissue types. The LD50 for each cell line was determined and the change in cell size determined. Flow cytometric analysis and western blotting were us...

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Detalles Bibliográficos
Autores principales: Morrison, R, Lodge, T, Evidente, A, Kiss, R, Townley, H
Formato: Journal article
Lenguaje:English
Publicado: Spandidos Publications 2017