Revisiting the thrifty gene hypothesis via 65 loci associated with susceptibility to type 2 diabetes.

We have investigated the evidence for positive selection in samples of African, European, and East Asian ancestry at 65 loci associated with susceptibility to type 2 diabetes (T2D) previously identified through genome-wide association studies. Selection early in human evolutionary history is predict...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Ayub, Q, Moutsianas, L, Chen, Y, Panoutsopoulou, K, Colonna, V, Pagani, L, Prokopenko, I, Ritchie, G, Tyler-Smith, C, McCarthy, M, Zeggini, E, Xue, Y
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2014