Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5
Reversible post-translational protein modifications such as SUMOylation add complexity to cardiac transcriptional regulation. The homeodomain transcription factor Nkx2-5/Csx is essential for heart specification and morphogenesis. It has been previously suggested that SUMOylation of lysine 51 (K51) o...
| المؤلفون الرئيسيون: | , , , , , , , , , , |
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| التنسيق: | Journal article |
| منشور في: |
Public Library of Science
2011
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