Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5

Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5

Reversible post-translational protein modifications such as SUMOylation add complexity to cardiac transcriptional regulation. The homeodomain transcription factor Nkx2-5/Csx is essential for heart specification and morphogenesis. It has been previously suggested that SUMOylation of lysine 51 (K51) o...

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Detalles Bibliográficos
Autores principales:	Costa, M, Lee, S, Furtado, M, Xin, L, Sparrow, D, Martinez, C, Dunwoodie, S, Kurtenbach, E, Mohun, T, Rosenthal, N, Harvey, R
Formato:	Journal article
Publicado:	Public Library of Science 2011

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