Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

Individuals with Down syndrome (DS) are predisposed to develop acute megakaryoblastic leukemia (AMKL), characterized by expression of truncated GATA1 transcription factor protein (GATA1s) due to somatic mutation. The treatment outcome for DS-AMKL is more favorable than for AMKL in non-DS patients. T...

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Detalles Bibliográficos
Main Authors:	Bourquin, J, Subramanian, A, Langebrake, C, Reinhardt, D, Bernard, O, Ballerini, P, Baruchel, A, Cavé, H, Dastugue, N, Hasle, H, Kaspers, G, Lessard, M, Michaux, L, Vyas, P, van Wering, E, Zwaan, C, Golub, T, Orkin, S
Formato:	Journal article
Idioma:	English
Publicado:	2006

Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

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