Clinical validation of optimised RT-LAMP for the diagnosis of SARS-CoV-2 infection

We have optimised a reverse transcription-loop-mediated isothermal amplification (RT-LAMP) assay for the detection of SARS-CoV-2 from extracted RNA for clinical application. We improved the stability and reliability of the RT-LAMP assay by the addition of a temperature-dependent switch oligonucleoti...

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Bibliographic Details
Main Authors: Lim, B, Ratcliff, J, Nawrot, D, Yu, Y, Sanghani, H, Hsu, C, Peto, L, Evans, S, Hodgson, S, Poncin, K, Vasudevan, S, Dai, S, Ren, S, Chang, H, Cui, Z, Simmonds, P, Huang, W, Andersson, M
Format: Journal article
Language:English
Published: Springer Nature 2021